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Nobuhiro Ohtake Selected Research

glycyrrhetyl 3-monoglucuronide

7/2008Down-regulation of a hepatic transporter multidrug resistance-associated protein 2 is involved in alteration of pharmacokinetics of glycyrrhizin and its metabolites in a rat model of chronic liver injury.
4/2007A possible involvement of 3-monoglucuronyl-glycyrrhetinic acid, a metabolite of glycyrrhizin (GL), in GL-induced pseudoaldosteronism.

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Nobuhiro Ohtake Research Topics

Disease

3Liddle Syndrome
08/2012 - 04/2007
2Chronic Hepatitis (Chronic Active Hepatitis)
07/2008 - 01/2005
1Obesity
03/2020
1Non-alcoholic Fatty Liver Disease
03/2020
1Ileus
04/2015
1Crohn Disease (Crohn's Disease)
06/2010
1Colitis
06/2010
1Liver Cirrhosis (Hepatic Cirrhosis)
07/2008
1Liver Diseases (Liver Disease)
05/2007
1Jaundice (Icterus)
05/2007
1Cholestasis
05/2007
1Hypokalemia
04/2007
1Body Weight (Weight, Body)
03/2007
1Hemorrhage
03/2007
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
03/2007
1Lung Injury
02/2002

Drug/Important Bio-Agent (IBA)

3Glycyrrhetinic Acid (Po 12)IBA
08/2012 - 04/2007
2AcidsIBA
08/2012 - 06/2010
2Glycyrrhizic Acid (Glycyrrhizin)IBA
07/2008 - 04/2007
2glycyrrhetyl 3-monoglucuronideIBA
07/2008 - 04/2007
1bofu-tsusho-sanIBA
03/2020
1Pharmaceutical PreparationsIBA
03/2020
1Organic Anion TransportersIBA
08/2012
1Oxidoreductases (Dehydrogenase)IBA
08/2012
1Calcitonin (Calcitonin, Eel)FDA LinkGeneric
06/2010
1Peptides (Polypeptides)IBA
06/2010
1AdrenomedullinIBA
06/2010
111-beta-Hydroxysteroid Dehydrogenase Type 2 (11 beta-Hydroxysteroid Dehydrogenase Type 2)IBA
07/2008
1Amino AcidsFDA Link
07/2008
1Choline (Choline Chloride)IBA
07/2008
111-beta-Hydroxysteroid Dehydrogenases (11beta Hydroxysteroid Dehydrogenase)IBA
07/2008
1CDAA (Randox)IBA
07/2008
1Multidrug Resistance-Associated Protein 2IBA
05/2007
1BilirubinIBA
05/2007
1NitratesIBA
03/2007
1Dinoprostone (PGE2)FDA Link
03/2007
1NitritesIBA
03/2007
1Indomethacin (Indometacin)FDA LinkGeneric
03/2007
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
03/2007
1shosaiko-to (TJ9)IBA
01/2005
1Interleukin-6 (Interleukin 6)IBA
02/2002
1CytokinesIBA
02/2002
1LipopolysaccharidesIBA
02/2002

Therapy/Procedure

2Traditional Medicine (Folk Remedies)
03/2020 - 04/2015
1Subcutaneous Injections
03/2007